The Holiday Inn Express Chillicothe Hotel is located off the Main St. Exit, from Rt 35, 50 and 23 near Historical downtown & shopping. Local companies include: Mead Paper, CSX Railroad, North Folk Southern Railway, Kenworth Trucking and the Adena Regional Medical Center. Hotel features include complimentary continental breakfast and free local phone calls. Enjoy a unique breakfast experience at our new Express Start Breakfast Bar served every morning featuring a selection of fruits, juices, cereals, breads/pastries, and even hardboiled eggs. We have also created the world's best tasting cinnamon roll. Visit Chillicothe, OH and stay smart at the Holiday Inn Express Hotel. This hotel is committed to providing accessible facilities under the American Disabilities Act. If your accessibility needs are not met, please contact the Hotel Manager on Duty. Should you require additional information regarding accessible facilities for guests with disabilities, please call 1-800-Holiday (U.S. and Canada) or contact the hotel directly. For the hearing impaired, TDD service is available at 1-800-238-5544 within the U.S. and Canada.