Our Holiday Inn Express Hotel ® Lake City is located in the eastern section of the South Carolina in Florence County at the junction of US Highway 378 & US Highway 52, central to major destination cities. Lake City is the perfect hotel when traveling with a group, for business or pleasures. Or, a great stop-over if your traveling to the historical cities and beaches of South Carolina, with accessibility to US Highway 52 and I-95. Charleston, SC ® 89 Mi Columbia, SC - 78 Mi Florence, SC - 25 Mi Myrtle Beach, S ...

Days Inn of Lake City SC is located on Highway 52, accessible from Rt 378 off I-95. We are a family friendly motel in a quite, peaceful area within walking distance to our downtown shops. Our property was recently awarded The Days Inn 5 Sunburst Rating for Quality. The hotel offers Free Daybreak Breakfast, Free High Speed Wireless Internet,Microwaves & Refrigerators in all rooms, Irons and Ironing-boards in all rooms, Meeting Facility-30 Classroom Style, Kings, Queens, and Double Rooms Available, King Jacuzzi Suite Avai ...